The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia

- Rammos, Alexandros, Gonzalez, Lara A. Neira, Weinberger, Daniel R., Mitchell, Kevin J., Nicodemus, Kristin K., Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T. R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David, Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu, Begemann, Martin, Belliveau, Richard, Bene, Judit, Cairns, Murray J., Henskens, Frans A., Kelly, Brian J., Loughland, Carmel M., Michie, Patricia T., Schall, Ulrich, Scott, Rodney J., Tooney, Paul A., Wu, Jing Qin

A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia

- Li, Wen, Fan, Chun Chieh, Mäki-Marttunen, Tuomo, Thompson, Wesley K., Schork, Andrew J., Bettella, Francesco, Ripke, Stephan, Neal, Benjamin M., Corvin, Aiden, Walters, James T. R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Cairns, Murray J., Henskens, Frans A., Kelly, Brian J., Michie, Patricia T., Schall, Ulrich, Scott, Rodney J., Tooney, Paul A., Wu, Jing Qin, Djurovic, Srdjan, Dale, Andrew M., Andreassen, Ole A., Wang, Yunpeng

Age at first birth in women is genetically associated with increased risk of schizophrenia

- Ni, Guiyan, Gratten, Jacob, Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Wray, Naomi R., Henskens, Frans A., Loughland, Carmel M., Michie, Patricia T., Schall, Ulrich, Scott, Rodney J., Bevilacqua, E, Bigdeli, TB, Black, DW, Bruggeman, R, Buccola, NG, Lee, Sang Hong, Buckner, RL, Byerley, W, Cahn, W, Cai, G, Campion, D, Cantor, RM, Carr, VJ, Carrera, N, Catts, SV, Chambert, KD, Ripke, Stephan, Chan, RCK, Chen, RYL, Chen, EYH, Cheng, W, Cheung, EFC, Chong, SA, Cloninger, CR, Cohen, D, Cohen, N, Cormican, P, Neale, Benjamin M., Craddock, N, Crowley, JJ, Curtis, D, Davidson, M, Davis, KL, Degenhardt, F, Del Favero, J, Demontis, D, Dikeos, D, Dinan, T, Corvin, Aiden, Djurovic, S, Donohoe, G, Drapeau, E, Walters, James T. R., Farh, Kai-How, Holmans, Peter A.

Analysis of shared heritability in common disorders of the brain

- Anttila, Verneri, Bulik-Sullivan, Brendan, Patsopoulos, Nikolaos A., Ripke, Stephan, Wei, Zhi, Yu, Dongmei, Lee, Phil H., Turley, Patrick, Grenier-Boley, Benjamin, Chouraki, Vincent, Kamatani, Yoichiro, Berr, Claudine, Finucane, Hilary K., Holliday, Elizabeth, Attia, John, Cairns, Murray, Loughland, Carmel, Schall, Ulrich, Henskens, Frans, Scott, Rodney, Reitz, C, Goate, AM, Huentelman, MJ, Walters, Raymond K., Ilyas Kamboh, M, Larson, EB, Rogaeva, E, George-Hyslop, PS, Hakonarson, H, Kukull, WA, Farrer, LA, Barnes, LL, Beach, TG, Yesim Demirci, F, Bras, Jose, Head, E, Hulette, CM, Jicha, GA, Kauwe, JSK, Kaye, JA, Leverenz, JB, Levey, AI, Lieberman, AP, Pankratz, VS, Poon, WW, Duncan, Laramie, Quinn, JF, Saykin, AJ, Schneider, LS, Smith, AG, Escott-Price, Valentina, Falcone, Guido J., Gormley, Padhraig, Malik, Rainer

Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

- Ni, Guiyan, Moser, Gerhard, Ripke, Stephan, Neale, Benjamin M., Corvin, Aiden, Walters, James T. R., Farh, Kai-How, Holmans, Peter A., Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A., Huang, Hailiang, Pers, Tune H., Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A., Henskens, Frans A., Loughland, Carmel A., Michie, Patricia T., Schall, Ulrich, Scott, Rodney J., Wray, Naomi R., Lee, S. Hong

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

- Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Boocock, James, Stahl, Eli A., Pavlides, Jennifer M. Whitehead, Mullins, Niamh, Charney, Alexander W., Ori, Anil P. S., Loohuis, Loes M. Olde, Domenici, Enrico, Di Florio, Arianna, Papiol, Sergi, Kalman, Janos L., Trubetskoy, Vassily, Adolfsson, Rolf, Agartz, Ingrid, Agerbo, Esben, Akil, Huda, Albani, Diego, Albus, Margot, Cairns, Murray J., Henskens, Frans A., Kelly, Brian J., Loughland, Carmel M., Michie, Patricia T., Schall, Ulrich, Scott, Rodney J., Tooney, Paul A., Wu, Jing Qin

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

- Marshall, Christian R., Howrigan, Daniel P., Gujral, Madhusudan, Brandler, William M., Malhotra, Dheeraj, Wang, Zhouzhi, Fuentes Fajarado, Karin V., Maile, Michelle S., Ripke, Stephan, Agartz, Ingrud, Albus, Margot, Alexander, Madeline, Merico, Daniele, Atkins, Joshua, Cairns, Murray J., Carr, Vaughan J., Henskens, Frans A., Kelly, Brian J., Loughland, Carmel L., Michie, Patricia T., Schall, Ulrich, Scott, Rodney J., Tooney, Paul A., Thiruvahindrapuram, Bhooma, Wu, Jing Qin, Wu, Wenting, Greer, Douglas S., Antaki, Douglas, Shetty, Aniket, Holmans, Peter A., Pinto, Dalila

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

- Franke, Barbara, Stein, Jason L., Ripke, Stephan, Anttila, Verneri, Hibar, Derrek P., van Hulzen, Kimm J. E.JE, Arias-Vasquez, Alejandro, Smoller, Jordan W., Nichols, Thomas E., Neale, Michael C., McIntosh, Andrew M., Lee, Phil, McMahon, Francis J., Meyer-Lindenberg, Andreas, Mattheisen, Manuel, Andreassen, Ole A., Gruber, Oliver, Sachdev, Perminder S., Roiz-Santiañez, Roberto, Saykin, Andrew J., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Enigma Consortium, Cairns, Murray J., Henskens, Frans A., Kelly, Brian J., Loughland, Carmel M., Michie, Patricia T., Schall, Ulli, Scott, Rodney J., Tooney, Paul A., Wu, Jing Qin, Hansen, Mitchell, Lee, Steve, Liu, Xiaochun

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

- Bigdeli, Tim B., Ripke, Stephan, Kirov, George, McQuillin, Andrew, Gurling, Hugh, Rujescu, Dan, Andreassen, Ole A., Werge, Thomas, Blackwood, Douglas H. R., Pato, Carlos N., Pato, Michele T., Malhotra, Anil K., Bacanu, Silviu-Alin, O'Donovan, Michael C., Kendler, Kenneth S., Fanous, Ayman H., Schizophrenia Working Group of the Psychiatric Genomics Consortium,, Henskens, Frans A., Lee, Sang Hong, Wray, Naomi R., Gejman, Pablo V., Rietschel, Marcella, Cichon, Sven, St Clair, David, Corvin, Aiden

Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts

- Ek, Weronica E., Reznichenko, Anna, Holliday, Elizabeth G., Houghton, Lesley, Gazouli, Maria, Karamanolis, George, Rappold, Gudrun, Burwinkel, Barbara, Surowy, Harald, Rafter, Joseph, Assadi, Ghazaleh, Li, Ling, Ripke, Stephan, Niesler, Beate, Zucchelli, Marco, Rivera, Natalia V., Schmidt, Peter T., Pedersen, Nancy L., Magnusson, Patrik, Talley, Nicholas J.

LD score regression distinguishes confounding from polygenicity in genome-wide association studies

- Bulik-Sullivan, Brendan K., Albus, M, Alexander, M, Amin, F, Bacanu, SA, Begemann, M, Belliveau, RA, Bene, J, Bergen, SE, Bruggeman, R, Bevilacqua, E, Bigdeli, TB, Black, DW, Buccola, NG, Buckner, RL, Byerley, W, Cahn, W, Cai, G, Cairns, MJ, Campion, D, Cantor, RM, Carr, VJ, Carrera, N, Catts, SV, Chambert, KD, Chan, RCK, Chen, RYL, Cohen, D, Chen, EYH, Cheng, W, Cheung, EFC, Chong, SA, Cloninger, CR, Cohen, N, Cormican, P, Craddock, N, Crespo-Facorro, B, Crowley, JJ, Curtis, D, Davidson, M, Davis, KL, Degenhardt, F, Del Favero, J, Loh, Po-Ru, Michie, Patricia T., Schall, Ulrich, Scott, Rodney J., Tooney, Paul A., Wu, Jing Qin, Patterson, Nick, Daly, Mark J., Price, Alkes L., Neale, Benjamin M., Finucane, Hilary K., Ripke, Stephan, Yang, Jian, Schizophrenia Working Group of the Psychiatric Genomics Consortium,, Cairns, Murray J., Henskens, Frans A., Kelly, Brian J., Loughland, Carmel M.

Modeling linkage disequilibrium increases accuracy of polygenic risk scores

- Vilhjálmsson, Bjarni J., Yang, Jian, Hayeck, Tristan, Won, Hong-Hee, Schizophrenia Working Group of the Psychiatric Genomics Consortium,, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study,, Finucane, Hilary K., Gusev, Alexander, Lindström, Sara, Ripke, Stephan, Genovese, Giulio, Loh, Po-Ru, Bhatia, Gaurav, Do, Ron

Partitioning heritability by functional annotation using genome-wide association summary statistics

- Finucane, Hilary K., Bulik-Sullivan, Brendan, Ripke, Stephan, Day, Felix R., ReproGen Consortium,, Schizophrenia Working Group of the Psychiatric Genomics Consortium,, The RACI Consortium,, Purcell, Shaun, Stahl, Eli, Lindstrom, Sara, Perry, John R. B., Okada, Yukinori, Gusev, Alexander, Raychaudhuri, Soumya, Daly, Mark J., Patterson, Nick, Neale, Benjamin M., Price, Alkes L., Henskens, Frans A., Loughland, Carmel M., Michie, Patricia T., Schall, Ulrich, Scott, Rodney J., Trynka, Gosia, Tooney, Paul A., Wu, Jing Qin, Reshef, Yakir, Loh, Po-Ru, Anttila, Verneri, Xu, Han, Zang, Chongzhi, Farh, Kyle

Biological insights from 108 schizophrenia-associated genetic loci

- Ripke, Stephan, Neale, Benjamin M., Pers, Tune H., Julià, Antonio, Kahn, René S., Kalaydjieva, Luba, Karachanak-Yankova, Sena, Karjalainen, Juha, Kavanagh, David, Keller, Matthew C., Kennedy, James L., Khrunin, Audrey, Kim, Yunjung, Agartz, Iingrid, Klovins, Janis, Knowles, James A., Konte, Bettina, Kucinskas, Vaidutis, Ausrele Kucinskiene, Zita, Kuzelova-Ptackova, Hana, Kähler, Anna K., Laurent, Claudine, Lee Chee Keong, Jimmy, Hong Lee, S., Agerbo, Esben, Legge, Sophie E., Lerer, Bernard, Li, Miaoxin, Li, Tao, Liang, Kung-Yee, Lieberman, Jeffrey, Limborska, Svetlana, Loughland, Carmel M., Lubinski, Jan, Lönnqvist, Jouko, Albus, Margot, Macek Jr, Milan, Magnusson, Patrik K. E., Maher, Brion S., Maier, Wolfgang, Mallet, Jacques, Marsal, Sara, Mattheisen, Manuel, Mattingsdal, Morten, McCarley, Robert W., McDonald, Colm, Alexander, Madeline, McIntosh, Andrew M., Meier, Sandra, Meijer, Carin J., Melegh, Bela, Melle, Iingrid, Mesholam-Gately, Raquelle I., Metspalu, Andres, Michie, Patricia T., Milani, Lili, Milanova, Virha, Amin, Farooq, Mokrab, Younes, Morris, Derek W., Mors, Ole, Murphy, Kieran C., Murray, Robin M., Myin-Germeys, Inez, Müller-Myhsok, Bertram, Nelis, Mari, Nenadic, Igor, Nertney, Deborah A., Bacanu, Silviu A., Nestadt, Gerald, Nicodemus, Kristin K., Nikitina-Zake, Liene, Nisenbaum, Laura, Nordin, Annelie, O'Callaghan, Eadbhard, O'Dushlaine, Colm, O'Neill, F. Anthony, Oh, Sang-Yun, Olincy, Ann, Begemann, Martin, Olsen, Line, Van Os, Jim, Psychosis Endophenotypes International Consortium, Pantelis, Christos, Papadimitriou, George N., Papiol, Sergi, Parkhomenko, Elena, Pato, Michele T., Paunio, Tiina, Pejovic-Milovancevic, Milica, Belliveau Jr, Richard A., Perkins, Diana O., Pietiläinen, Olli, Pimm, Jonathan, Pocklington, Andrew J., Powell, John, Price, Alkes, Pulver, Ann E., Purcell, Shaun M., Quested, Digby, Rasmussen, Henrik B., Bene, Judit, Reichenberg, Abraham, Reimers, Mark A., Richards, Alexander L., Roffman, Joshua L., Roussos, Panos, Ruderfer, Douglas M., Salomaa, Veikko, Sanders, Alan R., Schall, Ulrich, Schubert, Christian R., Corvin, Aiden, Bergen, Sarah E., Schulze, Thomas G., Schwab, Sibylle G., Scolnick, Edward M., Scott, Rodney J., Seidman, Larry J., Shi, Jianxin, Sigurdsson, Engilbert, Silagadze, Teimuraz, Silverman, Jeremy M., Sim, Kang, Bevilacqua, Elizabeth, Slominsky, Petr, Smoller, Jordan W., So, Hon-Cheong, Spencer, Chris C. A., Stahl, Eli A., Stefansson, Hreinn, Steinberg, Stacy, Stogmann, Elisabeth, Straub, Richard E., Strengman, Eric, Bigdeli, Tim B., Strohmaier, Jana, Scott Stroup, T., Subramaniam, Mythily, Suvisaari, Jaana, Svrakic, Dragan M., Szatkiewicz, Jin P., Söderman, Erik, Thirumalai, Srinivas, Toncheva, Draga, Tosato, Sarah, Black, Donald W., Veijola, Juha, Waddington, John, Walsh, Dermot, Wang, Dai, Wang, Qiang, Webb, Bradley T., Weiser, Mark, Wildenauer, Dieter B., Williams, Nigel M., Williams, Stephanie, Bruggeman, Richard, Witt, Stephanie H., Wolen, Aaron R., Wong, Emily H. M., Wormley, Brandon K., Simon Xi, Hualin, Zai, Clement C., Zheng, Xuebin, Zimprich, Fritz, Wray, Naomi R., Stefansson, Kari, Buccola, Nancy G., Visscher, Peter M., Welcome Trust Case-Control Consortium,, Adolfsson, Rolf, Andreassen, Ole A., Blackwood, Douglas H. R., Bramon, Elvira, Buxbaum, Joseph D., Børglum, Anders D., Cichon, Sven, Darvasi, Ariel, Buckner, Randy L., Domenici, Enrico, Ehrenreich, Hannelore, Esko, Tõnu, Gejman, Pablo V., Gill, Michael, Gurling, Hugh, Hultman, Christina M., Iwata, Nakao, Jablensky, Assen V., Jönsson, Erik G., Byerley, William, Kendler, Kenneth S., Kirov, George, Knight, Jo, Lencz, Todd, Levinson, Douglas F., Li, Qingqin S., Liu, Jianjun, Malhotra, Anil K., McCarroll, Steven A., McQuillin, Andrew, Cahn, Wiepke, Moran, Jennifer L., Mortensen, Preben B., Mowry, Bryan J., Nöthen, Markus M., Ophoff, Roel A., Owen, Michael J., Palotie, Aarno, Pato, Carlos N., Petryshen, Tracey L., Posthuma, Danielle, Cai, Guiqing, Rietschel, Marcella, Riley, Brien P., Rujescu, Dan, Sham, Pak C., Sklar, Pamela, St Clair, David, Weinberger, David R., Wendland, Jens R., Werge, Thomas, Daly, Mark J., Walters, James T. R., Campion, Dominique, Sullivan, Patrick F., O'Donovan, Michael C., Cantor, Rita M., Carr, Vaughan J., Carrera, Noa, Catts, Stanley V., Chambert, Kimberly D., Chan, Raymond C. K., Chen, Ronald Y. L., Chen, Eric Y. H., Cheng, Wei, Farh, Kai-How, Cheung, Eric F. C., Ann Chong, Siow, Robert Cloninger, C., Cohen, David, Cohen, Nadine, Cormican, Paul, Craddock, Nick, Crowley, James J., Curtis, David, Davidson, Michael, Holmans, Peter A., Davis, Kenneth L., Degenhardt, Franziska, Del Favero, Jurgen, Demontis, Ditte, Dikeos, Dimitris, Dinan, Timothy, Djurovic, Srdjan, Donohoe, Gary, Drapeau, Elodie, Duan, Jubao, Lee, Phil, Dudbridge, Frank, Durmishi, Naser, Eichhammer, Peter, Eriksson, Johan, Escott-Price, Valentina, Essioux, Laurent, Fanous, Ayman H., Farrell, Martilias S., Frank, Josef, Franke, Lude, Bulik-Sullivan, Brendan, Freedman, Robert, Freimer, Nelson B., Friedl, Marion, Friedman, Joseph I., Fromer, Menachem, Genovese, Giulio, Georgieva, Lyudmila, Giegling, Ina, Giusti-Rodríguez, Paola, Godard, Stephanie, Collier, David A., Goldstein, Jacqueline I., Golimbet, Vera, Gopal, Srihari, Gratten, Jacob, de Haan, Lieuwe, Hammer, Christian, Hamshere, Marian L., Hansen, Mark, Hansen, Thomas, Haroutunian, Vahram, Huang, Hailiang, Hartmann, Annette M., Henskens, Frans A., Herms, Stefan, Hirschhorn, Joel N., Hoffmann, Per, Hofman, Andrea, Hollegaard, Mads V., Hougaard, David M., Ikeda, Masashi, Joa, Inge

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis

- Goris, An, van Setten, Jessica, Diekstra, Frank, Ripke, Stephan, Patsopoulos, Nikolaos A., Sawcer, Stephen J., The International Multiple Sclerosis Genetics Consortium, van Es, Michael, The Australia and New Zealand MS Genetics Consortium, Andersen, Peter M., Melki, Judith, Meininger, Vincent, Hardiman, Orla, Landers, John E., Brown, Robert H., Shatunov, Aleksey, Leigh, Nigel, Al-Chalabi, Ammar, Shaw, Christopher E., Traynor, Bryan J., Chio, Adriano, Restagno, Gabriella, Mora, Gabriele, Ophoff, Roel A., Oksenberg, Jorge R., Van Damme, Philip, Compston, Alastair, Robberecht, Wim, Dubois, Bénédicte, van den Berg, Leonard H., De Jager, Philip L., Veldink, Jan H., de Bakker, Paul I. W.

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

- Gusev, Alexander, Lee, S. Hong, Kähler, Anna K., Hultman, Christina M., Purcell, Shaun M., McCarroll, Steven A., Daly, Mark, Pasaniuc, Bogdan, Sullivan, Patrick F., Neale, Benjamin M., Wray, Naomi R., Raychaudhuri, Soumya, Trynka, Gosia, Price, Alkes L., Finucane, Hilary, Vilhjálmsson, Bjarni J., Xu, Han, Zang, Chongzhi, Ripke, Stephan, Bulik-Sullivan, Brendan, Stahl, Eli

Genetic schizophrenia risk variants jointly modulate total brain and white matter volume

- Terwisscha van Scheltinga, Afke F., Schall, U, Michie, P, Carr, VJ, Scott, RJ, Bakker, Steven C., Kahn, René S., van Haren, Neeltje E. M., Derks, Eske M., Buizer-Voskamp, Jacobine E., Boos, Heleen B. M., Cahn, Wiepke, Hulshoff Pol, Hilleke E., Ripke, Stephan, Ophoff, Roel A.